News & Events
This page contains news and upcoming events that MRC-Holland will attend.

▷ No check payments accepted after the 30th of September
We will no longer accept check payments after the 30th of September 2019 because our bank will stop processing them. Payments can be settled by (international) bank transfer instead. For more information, see this page or contact

▷ SALSA HhaI volume and product code change
As of the 23rd of July 2019, SALSA HhaI will only be sold in a volume for 200 MLPA reactions (115 µl). The new volume has product code SMR50, and will cost €40. Product code SMR51 (65 µl for 100 reactions; €25) is no longer available.

The enzyme and its storage buffer have not been changed. Therefore, no additional validation experiments are required for existing customers.

▷ Reduced sloping with the new MLPA buffer
Starting March 2019, all shipments of SALSA MLPA Reagent Kits will include a modified SALSA MLPA Buffer. There will also be a small change in the storage buffer of the SALSA Ligase-65 enzyme. The new reagents strongly reduce peak pattern sloping that is frequently observed when DNA is extracted with a magnetic beads-based system. If you did not have this issue, the new reagents will not affect your results.

If you previously had sloping caused by a magnetic bead-based DNA extraction method and used the S4 Sample Stabiliser to improve your results, you most likely do not need to add the S4 Sample Stabiliser anymore. The new reagents will not eliminate other causes of sloping.

More information on the background of this change, its effects, the timeline and our validation study can be found on this page.

▷ Launch of SALSA Melt Assay: SALSA MC002 SMA Newborn Screen
The SALSA MC002 SMA Newborn Screen is the latest product from MRC Holland, and the only product targeted at newborn population screening for a disorder. The assay is simple to use and runs on standard equipment allowing easy implementation and streamlining SMA screening. For more information visit our launch page, or see our press release.

Come and Meet Us
If you are attending one of the following meetings, please stop by our booth to learn more about how MRC-Holland's products can be used to benefit your DNA or methylation analysis.

MRC-Holland booth at a congress
The upcoming MLPA workshops organised by MRC-Holland are listed on our Support Portal.
Improved Products
Multiple endocrine neoplasia (MEN) type1, 4; Pituitary adenoma predisposition syndrome
Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV); Feingold syndrome
Long QT syndrome (LQT)
Ehlers-Danlos syndrome type III (EDSIII); type IV (EDSIV)
Neurofibromatosis type 2 (NF2)
Tuberous sclerosis complex (TSC)
P337-TSC2 Confirmation
Tuberous sclerosis complex (TSC)
P125-Mitochondrial DNA
Mitochondrial DNA (mtDNA)
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