News & Events
Unsuitability of HhaI from Thermo Fisher Scientific, and possibly other suppliers, for MS-MLPA
17 November 2016
We have established that HhaI restriction enzymes manufactured by Thermo Fisher Scientific are incompatible with the MS-MLPA technique and can cause aberrant results as they are not inactivated by heat. The same may be true for certain HhaI (isoschizomers) from other suppliers. At this moment, the only restriction enzyme with proven suitability for MS- MLPA is the Promega (R6441) enzyme. Please find more information here.
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If you are attending one of the following meetings, please stop by our booth to learn more about how MLPA can be used to benefit your DNA, RNA or methylation analysis.
April 3-5 - AMP Global Congress. Berlin, Germany
May 27-30 - ESHG. Copenhagen, Denmark
The upcoming MLPA workshops organised by MRC-Holland are listed here.
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