[./productpagepag.html]
[./indexpag.html]
[./support_pagepag.html]
[./contactpagepag.html]
Copyright © 2005 - MRC-Holland
[./indexpag.html]
Home
-
[./productpagepag.html]
Products
-
[./support_pagepag.html]
Support
-
[./article_pagepag.html]
Articles
-
[./contactpagepag.html]
contact
[./order_infopag.html]
SALSA MLPA KIT P108 SCN5A
Brugada / long QT is an autosomal recessive disorder characterized by a distinct form of idiopathic ventricular fibrillation. The SCN5A gene product was found to have characteristics of a cardiac sodium channel. Mutations in the SCN5A gene can be the cause of the long QT and the Brugada syndromes as well as the PCCD disease (Progressive Cardiac Conduction Defect). Deletions in SCN5A are predicted to cause Brugada syndrome whereas duplications of this gene might be found in long QT syndrome patients. The SCN5A gene has 28 exons, spans 80 Kb of chromosomal sequence and is located on chromosome 3p22. This probemix contains probes that cover 17 out of the total 28 SCN5A exons. No probes are present for 11 exons that are very close to others for which a probe is present. Please note that a separate probemix, P114, is available for the KCNQ1 and KCNH2 genes.
Full mix description (word)
Full mix description (pdf)
Last Update Probe mix description: Vs 04; 15-04-2007 Last change in probe mix content: Lot 0407 (April 2007) Current Lot Number.: Lot 0407
IMPORTANT NOTICE: MLPA kits are sold by MRC-Holland for research purposes and to demonstrate the possibilities of the MLPA technique. This kit is not CE/FDA certified for use in diagnostic procedures. Salsa MLPA kits are supplied with all necessary buffers and enzymes. Purchase of the Salsa MLPA test kits includes a limited license to use these products for research purposes. The use of this MLPA kit requires a thermocycler with heated lid and sequence type electrophoresis equipment. Different fluorescent PCR primers are available. The MLPA technique has been first described in Nucleic Acid Research 30, e57 (2002)
References
[./products_prenatal_and_postnatalpag.html]
[./products_hereditary_cancer_researchpag.html]
[./products_various_syndromespag.html]
[./products_tumor_characterisationpag.html]
[./products_mrna_analysispag.html]
[./products_methylation_specificpag.html]
[./products_otherpag.html]
[./products_pharmacogeneticspag.html]
[./mlpapricelistpag.html]
[Web Creator] [LMSOFT]