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The MLPA products available are divided into different subcategories. Scroll through our different mixes to find your MLPA mix or gene(s) of interest, or just use the search function. MLPA kits for many more applications are currently being developed - please contact us at info@mlpa.com.
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Prenatal and Postnatal Analysis Detection of aberrant chromosomal copy numbers (13, 18, 21, X, Y ) and deletions/duplications in subtelomeric regions, both important causes of mental retardation.
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Hereditary Cancer Disorders Different types of neurofibromatosis, breast and colon cancer, and numerous other cancer-associated syndromes.
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Various Syndromes / Diseases Identification of a wide range of genetic disorders, including Duchenne/Becker, Cystic Fibrosis, Prader-Willi/Angelman, MEFV and DiGeorge syndrome, and many more.
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Tumor Characterisation Includes kits for HNSCC, breast, ovarian and cervical and lung cancer and oligodendroglioma. Additionally, we offer kits that screen for copy number changes and aberrant methylation patterns, both useful in tumor identification.
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mRNA Analysis Measuring of the mRNA profiles of human and mice.
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Methylation Detection Detection of copy number changes as well as for aberrant methylation patterns, e.g. methylation associated with tumor suppressor genes and Prader Willi/Angelman Syndrome.
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Other Products by MRC-Holland Separate MLPA reagents, as well as SALSA Polymerase (excellent subsitute for taq polymerase!), DQ- & DD-control fragments and Ligase-65 kits.
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Pharmacogenetics Products are in development.
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